Long-term effects of finasteride on prostate tissue composition
LS Marks, AW Partin, FJ Dorey, GJ Gormley, JI Epstein… - Urology, 1999 - Elsevier
Objectives. To determine the long-term effects of finasteride treatment on prostate tissue
composition; to relate these effects to clinical outcomes; and to test the hypothesis that
finasteride exerts a selective or preferential action on the transition zone. Methods. Nineteen
men with symptomatic benign prostatic hyperplasia (BPH) who completed a 6-month double-
blind trial of finasteride were enrolled in a 24-month open-label extension study of drug
responders. Magnetic resonance imaging and prostate biopsy for morphometric analysis …
composition; to relate these effects to clinical outcomes; and to test the hypothesis that
finasteride exerts a selective or preferential action on the transition zone. Methods. Nineteen
men with symptomatic benign prostatic hyperplasia (BPH) who completed a 6-month double-
blind trial of finasteride were enrolled in a 24-month open-label extension study of drug
responders. Magnetic resonance imaging and prostate biopsy for morphometric analysis …
